Organic Slant

  • Home
  • Shop
  • About
  • Facebook
  • Twitter
  • YouTube
  • Articles
  • Videos
  • Cartoons
  • Music
  • Links
  • Cancer
  • Environment
  • GMO’s
  • Health
  • Monsanto
  • Organic Foods
  • Super Foods
  • Fukushima
You are here: Home / Health / Probiotic-containing yogurt protects against microbiome changes that lead to antibiotic-induced diarrhea

Probiotic-containing yogurt protects against microbiome changes that lead to antibiotic-induced diarrhea

September 16, 2021 by Captain Organic Planet

Eating yogurt containing a particular strain of a well-studied probiotic appears to protect against harmful changes in the gut microbiome that are associated with antibiotic administration. That is the finding from a new randomized clinical trial, led by researchers at the University of Maryland School of Maryland (UMSOM), the University of Maryland School of Pharmacy (UMSOP), and Georgetown University Medical Center, which was recently published in the journal Nutrients.

The study found that yogurt containing the probiotic Bifidobacterium lactis BB-12 worked better than a placebo at maintaining the community of bacteria in the colon. The findings were so positive that the NIH funded an additional follow-up study.

“This finding provides important new insights into the mechanisms by which the probiotic, BB-12, may protect against antibiotic-associated diarrhea,” said study co-leader Claire Fraser, PhD, Professor of Medicine and Dean’s Endowed Professor of UMSOM and Director of the UMSOM Institute for Genome Sciences. “The new insights that we obtained regarding BB-12 reflect the multi-omics approach that we used in our study. This was possible only because of the different expertise that each of the principal investigators brought to this collaboration.”

In the study, 42 healthy volunteers were randomly assigned to consume a daily serving-size container of yogurt containing BB-12 along with a standard week-long regimen of the antibiotic amoxicillin clavulanate. They continued to consume the yogurt every day for a week after finishing the antibiotic. An additional 20 participants served as the control group and were randomly assigned to consume a daily yogurt without the probiotic for two weeks while also taking the same antibiotic regimen.

The researchers found that levels of the short chain fatty acid acetate, a beneficial metabolite produced by the microbiota, were reduced in all subjects after taking the antibiotic; however, the reduction in acetate was significantly greater in subjects receiving the placebo yogurt as compared with BB-12 supplemented yogurt. Acetate levels in subjects who received BB-12 also returned to baseline levels by 30 days, while they remained below baseline in subjects receiving the placebo.

About one in five people who take antibiotics develop antibiotic-associated diarrhea due to the drugs disrupting the healthy gut microbiome. Patients may stop taking their medications early after developing diarrhea, which could cause their original infection to persist. A small percentage may develop a life-threatening infection with the bacteria C. difficile, which can reside in the gut but is usually kept in check by good bacteria in the microbiome.

“An important reason why our study may have demonstrated positive results may be the timing of the probiotic administration on the day antibiotics were initiated by the study volunteers,” said study co-leader Daniel Merenstein, MD, Professor of Family Medicine and Director of Research Programs for the Department of Family Medicine at Georgetown University School of Medicine. “Starting the probiotic as early as possible, before the antibiotic symptoms have progressed, may result in a greater opportunity for the probiotic mechanisms to be expressed and may ultimately lead to more beneficial clinical outcomes.”

The researchers plan a follow-up study to further explore this question and decide when is the best time to consume a probiotic.

Related Posts

  • Honey as an antibiotic: Scientists identify a secret ingredient in honey that kills bacteria
  • Honey offers new approach to fighting antibiotic resistance
  • Recurrent UTIs linked to gut microbiome, chronic inflammation
  • A single course of antibiotics affects the gut microbiota of infants

Filed Under: Health Tagged With: antibiotic, diarrhea, microbiome, probiotic

Article Sources

  • https://www.medschool.umaryland.edu/news/2021/Probiotic-Containing-Yogurt-Protects-Against-Microbiome-Changes-That-Lead-to-Antibiotic-Induced-Diarrhea-Study-Finds.html
  • https://www.mdpi.com/2072-6643/13/8/2814

About Captain Organic Planet

C.O.P. (Captain Organic Planet) is on a mission to inform anyone with an open mind that our food is far from natural; it is synthetic and fake. I believe our food supply is contributing to most of our diseases. The sad thing is it doesn't end there. Everywhere around us are dangers; in our household, in our water, and in your shampoo. Every aspect of your life is contributing to your health, wellness, sickness and disease. Challenge Conventional Culture. Live Life With An Organic Slant. L.iving O.rganically V.ibrates E.nergy

VIDEOS

View All Videos

Popular

Is Towpath Trail At Cleveland Ohio Steelyard Commons Radioactive From Manhattan Project?

July 27, 2012 By Captain Organic Planet Filed Under: Cancer, Nuclear

14-Year Old Anti-GMO Activist Agitates Monsanto Schill, Kevin O’Leary

November 20, 2013 By Captain Organic Planet Filed Under: GMO's

Vegans At Increased Risk Of Developing Blood Clots And Atherosclerosis

January 5, 2017 By Captain Organic Planet Filed Under: Health

Follow Organic Slant

  • Facebook
  • Twitter
  • YouTube
Organic Slant
Tweets by organicslant

Organic Slant

  • Home
  • About
  • Shop
  • Contact
  • links
  • Advertise
  • Privacy Policy
  • Disclaimer
All Rights Reserved 2018

Organic Slant LLC is a participant in the Amazon Services LLC Associates Program, an affiliate advertising program designed to provide a means for sites to earn advertising fees by advertising and linking to Amazon.com.

  • Home
  • About
  • Shop
  • Contact
  • Articles
  • Videos
  • Cartoons
  • Media
  • Privacy Policy
  • Disclaimer
  • Advertise
  • Media
  • Facebook
  • Twitter
  • YouTube

· Organic Slant All Rights Reserved © 2025 ·