Pineapple Enzyme Bromelain has Cancer-Fighting Abilities

 (Organic Slant) Published in 2007 in the journal Planta Medica, researchers found that an enzyme extracted from pineapple stems known as bromelain was superior to the chemo-agent 5-fluorauracil in treating cancer in the animal model.

The researchers stated:

This antitumoral effect [bromelain] was superior to that of 5-FU [5-fluorouracil], whose survival index was approximately 263 %, relative to the untreated control. (view study)

As a highly toxic, fluoride-bound form of the nucleic acid uracil, a normal component of RNA, the drug is supposed to work by tricking more rapidly dividing cells — which include both cancer and healthy intestinal, hair follicle, and immune cells — into taking it up, thereby inhibiting (read: poisoning) RNA replication enzymes and RNA synthesis.

The material safety data sheet (MSDS) for 5-FU states:

The dose at which 50% of the animals given the drug die is 115mg/kg, or the equivalent of 7.8 grams for a 150 lb adult human.

Keep in mind that a 7.5 gram dose of 5-FU, which is the weight of 3 pennies, would kill 50% of the humans given it. Bromelain’s MSDS, on the other hand, states the LD50 to be 10,000 mg/kg, or the equivalent 1.5 lbs of bromelain for a 150lb adult, which means it is 3 orders of magnitude safer!

How then, can something as innocuous as the enzyme from the stem/core of a pineapple be superior to a drug that millions of cancer patients over the past 40 years have placed their hopes of recovery on, as well as spending billions of dollars on in the process?

Bromelain is a proteolytic enzyme (an enzyme that digests proteins). In the Planta Medica study, it was injected directly into the abdominal cavity. Getting enzymes from your digestive tract into your bloodstream isn’t as easy as it would seem, as enzymes are very susceptible to denaturing and must be helped to survive the highly acidic environment in your stomach. They are often given an “enteric coating” to help them survive the journey through your digestive tract.

There is a well-known effect associated with a wide range of natural compounds called “selective cytotoxicity,” whereby they are able to induce programmed cell death (the graceful self-disassembly known as apoptosis) within the cancer cells, while leaving healthy cells and tissue unharmed. No FDA-approved chemotherapy drug on the market today has this indispensable property, which is why cancer treatment is still in the dark ages, often destroying the quality of life, and accelerating the death of those who undergo it, often unwittingly. When a person dies following conventional cancer treatment it is all too easy to “blame the victim” and simply write that patient’s cancer off as “chemo-resistant,” or “exceptionally aggressive,” when in fact the non-selective nature of the chemotoxic agent is what ultimately lead to their death.